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Regulatory Considerations TB500 is not approved for human use by regulatory agencies in many countries, presenting legal and quality control challenges

We also removed the cost report data of 6 hospitals because these hospitals had cost report data that were not complete (missing aggregate OPPS payments, missing aggregate cost data, or missing both), so that all cost reports in the study would have both the payment and cost data necessary to calculate a PCR for each hospital, leading to an analytic file of 3,341 hospitals with cost report data

Both are trisulfides, a class of molecules containing three sulfur atoms connected in sequence